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Article

Proteogenomics of glioblastoma associates molecular patterns with survival

1 Mar 2021

Abstract excerpt

Glioblastoma (GBM) is the most aggressive form of glioma, with poor prognosis exhibited by most patients, and a median survival time of less than 2 years. We assemble a cohort of 87 GBM patients whose survival ranges from less than 3 months and up to 10 years and perform both high-resolution mass spectrometry proteomics and RNA sequencing (RNA-seq). Integrative analysis of protein expression, RNA expression, and...

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PMID: 33657365
DOI: 10.1016/j.celrep.2021.108787

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