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Article

The role of ASXL1 mutations and ASXL1 CircRNAs in cancer.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Feb 2024

Jafarbeik-Iravani Narges, Kolahdozan Sara, Esmaeili Rezvan

Abstract excerpt

BACKGROUND: Mutations in the Additional Sex Combs Like 1 (ASXL1) gene were first reported in myelodysplastic syndromes. Recent studies have clarified the relationship between ASXL1 mutations and the development of cancers. OBJECTIVE: This study aims to review the roles of ASXL1 and ASXL1 CircRNAs, such as epigenetic regulation, chromatin modification, and transcription factor function in malignancies. METHOD:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38193494
DOI: 10.1080/1354750X.2024.2304187

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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