Article
Epigenetic regulation by ASXL1 in myeloid malignancies.
International journal of hematology - 1 Jun 2023
Yang Feng-Chun, Agosto-Peña Joel
Abstract excerpt
Myeloid malignancies are clonal hematopoietic disorders that are comprised of a spectrum of genetically heterogeneous disorders, including myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN), chronic myelomonocytic leukemia (CMML), and acute myeloid leukemia (AML). Myeloid malignancies are characterized by excessive proliferation, abnormal self-renewal, and/or differentiation defects of...
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