Article

Comprehensive Genomic Profiling Reveals Molecular Subsets of ASXL1-Mutated Myeloid Neoplasms

2022-10-11

Abstract excerpt

<title>Abstract</title> <p><italic>ASXL1</italic> is a dynamic epigenetic regulator frequently mutated in myeloid neoplasia. However, a large-scale analysis of patients with <italic>ASXL1</italic>-mutated myeloid disease has not been performed to date. We retrospectively analyzed comprehensive genomic profiling results from clinical samples from 6,043 adult patients to characterize the spectrum of <italic>ASXL1</...

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Literature Corpus work: 5ab78f23-6ca5-55ea-b260-c04a44de9205
DOI: 10.21203/rs.3.rs-2139047/v1

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