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Article

Genetic contribution of reproductive traits to risk of uterine leiomyomata: a large-scale, genome-wide, cross-trait analysis.

American journal of obstetrics and gynecology - 1 Apr 2024

Xiao Changfeng, Wu Xueyao, Gallagher C Scott, Rasooly Danielle, Jiang Xia, Morton Cynthia Casson

Abstract excerpt

BACKGROUND: Although phenotypic associations between female reproductive characteristics and uterine leiomyomata have long been observed in epidemiologic investigations, the shared genetic architecture underlying these complex phenotypes remains unclear. OBJECTIVE: We aimed to investigate the shared genetic basis, pleiotropic effects, and potential causal relationships underlying reproductive traits (age at...

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PMID: 38191017
DOI: 10.1016/j.ajog.2023.12.040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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