Article
Joint Genome-Wide Association Analyses Identified 49 Novel Loci For Age at Natural Menopause.
The Journal of clinical endocrinology and metabolism - 18 Aug 2021
Zhang Lei, Wei Xin-Tong, Niu Jun-Jie, Lin Zi-Xuan, Xu Qian, Ni Jing-Jing, Zhang Wan-Lin, Han Bai-Xue, Yan Shan-Shan, Feng Gui-Juan, Zhang Hong, Yang Xiao-Lin, Zhang Zi-Jia, Hai Rong, Ren Hai-Gang, Zhang Feng, Pei Yu-Fang
Abstract excerpt
BACKGROUND: Age at natural menopause (ANM) is an important index for women's health. Either early or late ANM is associated with a series of adverse outcomes later in life. Despite being an inheritable trait, its genetic determinant has not yet been fully understood. METHODS: Aiming to better characterize the genetic architecture of ANM, we conducted genome-wide association study (GWAS) meta-analyses in...
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