Article
Genetic Association Studies in Uterine Fibroids: Risk Alleles Presage the Path to Personalized Therapies.
Seminars in reproductive medicine - 1 Jul 2016
Gallagher C Scott, Morton Cynthia C
Abstract excerpt
Uterine leiomyoma (UL) is the most common tumor of the female reproductive system. Epidemiological analyses, including familial aggregation, twin studies, and racial discrepancies in disease prevalence and morbidity, indicated genetic factors influence risk for developing UL. Genome-wide association studies (GWASs) are a powerful method for identifying genetic variants that are associated with elevated risk for a...
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