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Article

PD-L1 blockade TAM-dependently potentiates mild photothermal therapy against triple-negative breast cancer.

Journal of nanobiotechnology - 11 Dec 2023

Wang Chao, Xu Yong-Hong, Xu Hua-Zhen, Li Ke, Zhang Quan, Shi Lin, Zhao Li, Chen Xiao

Abstract excerpt

The present work was an endeavor to shed light on how mild photothermia possibly synergizes with immune checkpoint inhibition for tumor therapy. We established mild photothermal heating protocols to generate temperatures of 43 °C and 45 °C in both in vitro and in vivo mouse 4T1 triple-negative breast cancer (TNBC) models using polyglycerol-coated carbon nanohorns (CNH-PG) and 808 nm laser irradiation. Next, we...

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Identifiers

PMID: 38082443
DOI: 10.1186/s12951-023-02240-3
PMCID: PMC10712197

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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