Article

Synergy of nanodiamond-doxorubicin conjugates and PD-L1 blockade effectively turns tumor associated macrophages against tumor cells

2021-07-14

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Tumor-associated macrophages (TAM) are the most abundant stromal cells in the tumor microenvironment. Turning the TAM against their host tumor cells is an intriguing therapeutic strategy particularly attractive for patients with immunologically “cold” tumors. This concept was mechanistically demonstrated on in vitro human and murine lung cancer cells and their c...

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Literature Corpus work: 0669bc4d-5b35-587e-a9e6-6afa0cc044d3
DOI: 10.21203/rs.3.rs-715564/v1

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