Article

Ultrasound-Activated Nanobubbles Induce Durable Systemic Antitumor Immunity

2026-03-27

Abstract excerpt

<h4>ABSTRACT</h4> Clinical outcomes in aggressive breast cancer vary widely, in part because the tumor microenvironment is structured to exclude immune infiltration. Low antigen load, dysfunctional antigen-presenting cells, T cell exclusion and exhaustion, and a stiff extracellular matrix that physically restricts immune cell trafficking work together to form a suppressive barrier that current immunotherapies str...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 156ba5c4-4ea4-59f3-9ed1-ac7263526cc2
DOI: 10.64898/2026.03.25.714247

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Ultrasound-Activated Nanobubbles Induce Durable Systemic Antitumor ImmunityDOI 10.64898/2026.03.25.714247Read

Simulation-guided non-thermal low-intensity ultrasound reprograms the tumor immune microenvironment and engages systemic antitumor immunity in a syngeneic orthotopic mouse model of breast cancerSemantic proximity Read

Laser nanobubbles induce immunogenic cell death in breast cancerSemantic proximity Read

Magnetic field-induced ER stress reprograms the tumor microenvironment to improve triple-negative breast cancer survivalSemantic proximity Read

Small extracellular vesicles promote stiffness-mediated metastasisSemantic proximity Read

Strengthening Antisense Oligonucleotide-Mediated Anti-Tumor Immunity via Metal-Organic Framework NanoparticlesSemantic proximity Read

Nanomedicine for Cancer and Autoimmune ImmunotherapySemantic proximity Read

LIFUS-Driven Engineered Bacteria Reprogram Immunosuppressive Niches via Mechano-NOTCH SignalingSemantic proximity Read

Programable Albumin-Hitchhiking Nanobodies Enhance the Delivery of STING Agonists to Potentiate Cancer ImmunotherapySemantic proximity Read

VEGFR2 blockade converts thermally ablative focused ultrasound into a potent driver of T cell-dependent anti-tumor immunitySemantic proximity Read

Ultrasound-mediated PLGA-PEI Nanobubbles Carrying STAT6 SiRNA Enhances NSCLC Treatment via Repolarizing Tumor-associated Macrophages from M2 to M1 Phenotypes.Semantic proximity Read

Supramolecular Biomimetic Topology: Macrophage-Engaged Neoadjuvant Platform for Preoperative ImmunotherapySemantic proximity Read

Supramolecular Biomimetic Topology: Macrophage-Engaged Neoadjuvant Platform for Preoperative ImmunotherapySemantic proximity Read