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Article

A homologous-targeting "nanoconverter" with variable size for deep tumor penetration and immunotherapy.

Journal of materials chemistry. B - 11 Mar 2021

Cong Cong, Jiaxin Bian, Liu Xiaokang, Zhang Xinyue, Fu Yihan, Li Zhuo, Xu Zichuang, Wei Shipan, Wang Desong, Gao Dawei

Abstract excerpt

Tumor-associated immunosuppression, as a key barrier, prevents immunotherapy-resistant tumors. In this study, an ingenious "nanoconverter" was designed to convert immunosuppression into immunoactivation, which was a C6-ceramide (C6)-modified tumor cytomembrane-coated polydopamine-paclitaxel system (PTX/PDA@M-C6). The co-administration of C6-ceramide and tumor cytomembrane changed an adaptive immune state to an...

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Identifiers

PMID: 33621309
DOI: 10.1039/d0tb02908d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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