Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Higher TP53 somatic mutation prevalence from liquid biopsy analysis in ever smoker non-small-cell lung cancer patients.

Mutation research - 1 Jan 2000

Erdem Haktan Bağış, Alay Mustafa Tarık, Özdemir Zeynep, Çevik Ezgi, Ateş Öztürk, Karaçin Cengiz, Şahin İbrahim, Doğan Mutlu, Bahsi Taha

Abstract excerpt

OBJECTIVE: Cigarette smoking is a primary risk factor, linked to 80% of LC deaths. TP53, a key gene, is implicated in various cancers, with TP53 alterations in 36.7% of cancers. This research aims to investigate TP53 mutations detected in NSCLC patients by liquid biopsy and explore the relationship between these mutations and smoking history. MATERIAL AND METHOD: The study enrolled a total of 340 patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to Class I Phosphatidylinositol 3-Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ErbB Receptors

Share to Liquid Biopsy

Share to Lung Neoplasms

Share to Smokers

Share to Smoking

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 38071953
DOI: 10.1016/j.mrfmmm.2023.111847

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Higher TP53 somatic mutation prevalence from liquid biopsy analysis in ever smoker non-small-cell lung cancer patients.PMID 38071953Read ↗

TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer PatientsSemantic proximity Read ↗

Spectrum of germline mutations in smokers and non-smokers in Brazilian non-small-cell lung cancer (NSCLC) patients.Semantic proximity Read ↗

TP53 Mutation Mapping in Advanced Non-Small Cell Lung Cancer: A Real-World Retrospective Cohort Study.Semantic proximity Read ↗

Targeted next-generation sequencing of TP53 in oral tongue carcinoma from non-smokers.Semantic proximity Read ↗

Frequent mutations in EGFR, KRAS and TP53 genes in human lung cancer tumors detected by ion torrent DNA sequencing.Semantic proximity Read ↗

Genomic landscape and prognosis of patients with TP53-mutated non-small cell lung cancerSemantic proximity Read ↗

Smoking, p53 mutation, and lung cancer.Semantic proximity Read ↗

Tobacco Smoking-Related Mutational Signatures in Classifying Smoking-Associated and Nonsmoking-Associated NSCLC.Semantic proximity Read ↗

Lung adenocarcinomas with isolated TP53 mutation: A comprehensive clinical, cytopathologic and molecular characterization.Semantic proximity Read ↗

TP53 mutation prevalence in normal airway epithelium as a biomarker for lung cancer riskSemantic proximity Read ↗

Disruptive and Truncating TP53 Mutations Are Associated with African-Ancestry and Worse Prognosis in Brazilian Patients with Lung Adenocarcinoma.Semantic proximity Read ↗

TP53 and KRAS mutation load and types in lung cancers in relation to tobacco smoke: distinct patterns in never, former, and current smokers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.