Article
Smoking, p53 mutation, and lung cancer.
Molecular cancer research : MCR - 1 Jan 2014
Gibbons Don L, Byers Lauren A, Kurie Jonathan M
Abstract excerpt
This issue marks the 50th anniversary of the release of the U.S. Surgeon General's Report on Smoking and Health. Perhaps no other singular event has done more to highlight the effects of smoking on the development of cancer. Tobacco exposure is the leading cause of cancers involving the oral cavity, conductive airways, and the lung. Owing to the many carcinogens in tobacco smoke, smoking-related malignancies have...
Topics
- Animals
- DNA Damage
- Disease Progression
- Humans
- Lung
- Lung Neoplasms
- Mice
- Mutation
- Smoking
- Tumor Suppressor Protein p53
- Tobacco Products