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Article

TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer Patients

11 May 2016

Abstract excerpt

BACKGROUND: TP53 mutations are among the most common mutations found in lung cancers, identified as an independent prognostic factor in many types of cancers. The purpose of this study was to investigate the frequency and prognostic impact of TP53 mutations in never-smokers and in different histological subtypes of lung cancer. METHODS: We analyzed tumor tissue from 394 non-small cell carcinomas including...

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Identifiers

PMID: 27242894
DOI: 10.3389/fgene.2016.00085

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