Article
Polygenic Risk of Mental Disorders and Subject-Specific School Grades.
Biological psychiatry - 1 Aug 2024
Jefsen Oskar Hougaard, Holde Katrine, McGrath John J, Rajagopal Veera Manikandan, Albiñana Clara, Vilhjálmsson Bjarni Jóhann, Grove Jakob, Agerbo Esben, Yilmaz Zeynep, Plana-Ripoll Oleguer, Munk-Olsen Trine, Demontis Ditte, Børglum Anders, Mors Ole, Bulik Cynthia M, Mortensen Preben Bo, Petersen Liselotte Vogdrup
Abstract excerpt
BACKGROUND: Education is essential for socioeconomic security and long-term mental health; however, mental disorders are often detrimental to the educational trajectory. Genetic correlations between mental disorders and educational attainment do not always align with corresponding phenotypic associations, implying heterogeneity in the genetic overlap. METHODS: We unraveled this heterogeneity by investigating...
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