Article
Polygenic scores for schizophrenia and educational attainment are associated with behavioural problems in early childhood in the general population.
Journal of child psychology and psychiatry, and allied disciplines - 1 Jan 2018
Jansen Philip R, Polderman Tinca J C, Bolhuis Koen, van der Ende Jan, Jaddoe Vincent W V, Verhulst Frank C, White Tonya, Posthuma Danielle, Tiemeier Henning
Abstract excerpt
BACKGROUND: Genome-wide association studies in adults have identified numerous genetic variants related to psychiatric disorders and related traits, such as schizophrenia and educational attainment. However, the effects of these genetic variants on behaviour in the general population remain to be fully understood, particularly in younger populations. We investigated whether polygenic scores of five psychiatric...
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