Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Schizophrenia risk alleles and neurodevelopmental outcomes in childhood: a population-based cohort study.

The lancet. Psychiatry - 1 Jan 2017

Riglin Lucy, Collishaw Stephan, Richards Alexander, Thapar Ajay K, Maughan Barbara, O'Donovan Michael C, Thapar Anita

Abstract excerpt

BACKGROUND: Schizophrenia typically onsets after puberty but is often preceded by observable childhood neurodevelopmental impairments. Whether these childhood antecedents index genetic liability is unknown. We used polygenic risk scores derived from a patient discovery sample as indicators of the genetic liability of schizophrenia. Our aim was to identify the early childhood manifestations of this liability in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Multifactorial Inheritance

Share to Neurodevelopmental Disorders

Share to United Kingdom

Source

Identifiers

PMID: 27932233
DOI: 10.1016/S2215-0366(16)30406-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Schizophrenia risk alleles and neurodevelopmental outcomes in childhood: a population-based cohort study.PMID 27932233Read ↗

Genetic liability for schizophrenia and childhood psychopathology in the general populationSemantic proximity Read ↗

Genetic Liability for Schizophrenia and Childhood Psychopathology in the General Population.Semantic proximity Read ↗

Phenotypic Manifestation of Genetic Risk for Schizophrenia During Adolescence in the General Population.Semantic proximity Read ↗

Polygenic scores for schizophrenia and educational attainment are associated with behavioural problems in early childhood in the general population.Semantic proximity Read ↗

Schizophrenia polygenic risk score and prepubertal developmental impairments.Semantic proximity Read ↗

Genetic Overlap Between Schizophrenia and Developmental Psychopathology: Longitudinal and Multivariate Polygenic Risk Prediction of Common Psychiatric Traits During DevelopmentSemantic proximity Read ↗

Using Genetics to Examine a General Liability to Childhood Psychopathology.Semantic proximity Read ↗

Genetic Risk and Resilience for Schizophrenia Stratified by Perinatal Gene Expression Predict Adult Cognitive PerformanceSemantic proximity Read ↗

Independent versus joint effects of polygenic or family-based schizophrenia risk in diverse ancestry youth in the ABCD study.Semantic proximity Read ↗

Neuropsychological performance and family history in children at age 7 who develop adult schizophrenia or bipolar psychosis in the New England Family Studies.Semantic proximity Read ↗

The use of polygenic risk scores to identify phenotypes associated with genetic risk of schizophrenia: Systematic review.Semantic proximity Read ↗

The impact of schizophrenia and mood disorder risk alleles on emotional problems: investigating change from childhood to middle age.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.