Article
Neurodevelopmental and genetic determinants of exposure to adversity among youth at risk for mental illness.
Journal of child psychology and psychiatry, and allied disciplines - 1 May 2020
Zwicker Alyson, MacKenzie Lynn E, Drobinin Vladislav, Bagher Amina M, Howes Vallis Emily, Propper Lukas, Bagnell Alexa, Abidi Sabina, Pavlova Barbara, Alda Martin, Denovan-Wright Eileen M, Uher Rudolf
Abstract excerpt
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) and lower cognitive ability have been linked with increased likelihood of exposure to adversity. We hypothesized that these associations may be partly due to genetic factors. METHODS: We calculated polygenic scores for ADHD and intelligence and assessed psychopathology and general cognitive ability in a sample of 297 youth aged 5-27 years enriched for...
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