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Article

Adenoviruses vectored hepatitis C virus vaccine cocktails induce broadly specific immune responses against multi-genotypic HCV in mice.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Jan 2024

Luo Shengxue, Zhang Panli, Wang Yilin, Huang Yunzhu, Ma Xiaorui, Deng Qitao, Zou Peng, Wang Cong, Zhang Ling, Li Yiping, Fu Yongshui, Li Tingting, Li Chengyao

Abstract excerpt

BACKGROUND: Hepatitis C virus (HCV) vaccines are an urgent need to prevent hepatitis C and its further progression of hepatocellular carcinoma. Since the promising T cell based chimpanzee adenovirus and modified vaccinia virus Ankara vectorial HCV vaccines were failed in clinical phase II trial, the vaccine designs to improve protection efficacy in combination of cellular and humoral immunity have been...

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Identifiers

PMID: 38056238
DOI: 10.1016/j.biopha.2023.115901

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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