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Prime-boost vaccination of mice and Rhesus macaques with two novel adenovirus vectored COVID-19 vaccine candidates

2020-09-29

Abstract excerpt

<h4>ABSTRACT</h4> COVID-19 vaccines are being developed urgently worldwide, among which single-shot adenovirus vectored vaccines represent a major approach. Here, we constructed two novel adenovirus vectored COVID-19 vaccine candidates on simian adenovirus serotype 23 (Sad23L) and human adenovirus serotype 49 vectors (Ad49L) carrying the full-length gene of SARS-CoV-2 spike protein (S), designated Sad23L-nCoV-S a...

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Identifiers and source

Literature Corpus work
743c3e47-cd5b-5bf5-bc51-81559cd99a4b
DOI
10.1101/2020.09.28.311480
Open publication

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