Article
A heterologous prime/boost vaccination strategy enhances the immunogenicity of therapeutic vaccines for hepatitis C virus.
The Journal of infectious diseases - 1 Sept 2013
Fournillier Anne, Frelin Lars, Jacquier Emilie, Ahlén Gustaf, Brass Anette, Gerossier Estelle, Holmström Fredrik, Broderick Kate E, Sardesai Niranjan Y, Bonnefoy Jean-Yves, Inchauspé Geneviève, Sällberg Matti
Abstract excerpt
BACKGROUND: We explored the concept of heterologous prime/boost vaccination using 2 therapeutic vaccines currently in clinical development aimed at treating chronically infected hepatitis C virus (HCV) patients: prime with a DNA-based vaccine expressing HCV genotype 1a NS3/4A proteins (ChronVac-C...
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