Article
Induction of Genotype Cross-Reactive, Hepatitis C Virus-Specific, Cell-Mediated Immunity in DNA-Vaccinated Mice.
Journal of virology - 15 Apr 2018
Wijesundara Danushka K, Gummow Jason, Li Yanrui, Yu Wenbo, Quah Benjamin J, Ranasinghe Charani, Torresi Joseph, Gowans Eric J, Grubor-Bauk Branka
Abstract excerpt
A universal hepatitis C virus (HCV) vaccine should elicit multiantigenic, multigenotypic responses, which are more likely to protect against challenge with the range of genotypes and subtypes circulating in the community. A vaccine cocktail and vaccines encoding consensus HCV sequences are attractive approaches to achieve this goal. Consequently, in a series of mouse vaccination studies, we compared the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
