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Relationship of the transcription factor MexT to quorum sensing and virulence in Pseudomonas aeruginosa

30 Nov 2023

Abstract excerpt

ABSTRACT Quorum sensing (QS) regulates expression of many virulence genes in the opportunistic human pathogen Pseudomonas aeruginosa . There are two acyl-homoserine lactone (AHL) QS circuits, LasI-R and RhlI-R, which together activate expression of hundreds of genes in a cell density-dependent manner. There is also an inter-related non-AHL QS circuit, the Pseudomonas Quinolone Signal (PQS) circuit. Studies of the...

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PMID: 38032211
DOI: 10.1128/jb.00226-23

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