Article

Modulation of the <i>Pseudomonas aeruginosa</i> quorum sensing cascade by MexT-regulated factors

2025-03-17

Abstract excerpt

Pseudomonas aeruginosa (Pa) uses quorum sensing (QS), a cell-cell communication system that enables it to sense cell density and to alter gene expression. Pa has three complete QS circuits controlled by the regulators LasR, RhlR, and PqsR, that together activate hundreds of genes. In the well-studied strain PAO1, QS is organized hierarchically, with PqsR and RhlR activity dependent on LasR. This hierarchy depends...

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Literature Corpus work: e3eb6fbf-ad28-5715-8eb8-3857cb0a8765
DOI: 10.1101/2025.03.17.643737

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