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Article

The regulatory repertoire of Pseudomonas aeruginosa AmpC ß-lactamase regulator AmpR includes virulence genes.

PloS one - 1 Jan 2012

Balasubramanian Deepak, Schneper Lisa, Merighi Massimo, Smith Roger, Narasimhan Giri, Lory Stephen, Mathee Kalai

Abstract excerpt

In Enterobacteriaceae, the transcriptional regulator AmpR, a member of the LysR family, regulates the expression of a chromosomal β-lactamase AmpC. The regulatory repertoire of AmpR is broader in Pseudomonas aeruginosa, an opportunistic pathogen responsible for numerous acute and chronic infections including cystic fibrosis. In addition to regulating ampC, P. aeruginosa AmpR regulates the sigma factor AlgT/U and...

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Identifiers

PMID: 22479525
DOI: 10.1371/journal.pone.0034067
PMCID: PMC3315558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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