Article

Plasticity in a bacterial global regulatory switch that drives a shift in antibiotic resistance and virulence

2025-06-09

Abstract excerpt

Antibiotic resistance and expression of virulence factors can impact the outcome of infection by Pseudomonas aeruginosa . Pathogenesis is often modelled using the P. aeruginosa PAO1 reference strain but laboratory lineages vary in the sequence and activity of MexT, a global regulator impacting virulence, biofilm formation and ciprofloxacin resistance. We defined the impact of active versus inactive MexT in PAO1...

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Literature Corpus work: c0b35a8a-ead8-58ec-94c2-632f82605331
DOI: 10.1101/2025.06.09.658697

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