Article

Atypical BlaIR Two-Component System in <i>Pseudomonas aeruginosa</i> Regulates Virulence but not β-Lactam Resistance

2026-08-07

Abstract excerpt

With the rise of antimicrobial resistance, anti-virulence therapeutics are a viable alternative to circumvent resistance pressures. Hypothetical genes and proteins are an under-studied source of potential virulence factor targets. We performed bioinformatic analyses to identify conserved hypothetical genes enriched in pathogenic Pseudomonas aeruginosa but not in non-pathogenic strains. This analysis identified an...

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Literature Corpus work: ea9bc3f1-85ae-5c84-a2b7-148feab36f09
DOI: 10.64898/2026.08.03.742534

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