Article
Quorum-sensing regulation of a copper toxicity system in Pseudomonas aeruginosa.
Journal of bacteriology - 1 May 2010
Thaden Joshua T, Lory Stephen, Gardner Timothy S
Abstract excerpt
The LasR/LasI quorum-sensing system in Pseudomonas aeruginosa influences global gene expression and mediates pathogenesis. In this study, we show that the quorum-sensing system activates, via the transcriptional regulator PA4778, a copper resistance system composed of 11 genes. The quorum-sensing global regulator LasR was recently shown to directly activate transcription of PA4778, a cueR homolog and a MerR-type...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
