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Article

Inactivation of MexT in Pseudomonas aeruginosa PAO1 destabilizes cooperation and favors the emergence of a unique quorum sensing variant.

Journal of bacteriology - 21 May 2026

Bellamoroso Kiana R, Kostylev Maxim, Smalley Nicole E, Greenberg E Peter, Dandekar Ajai A

Abstract excerpt

Pseudomonas aeruginosa, an opportunistic Gram-negative pathogen, uses a cell-cell signaling system called quorum sensing to coordinate group behaviors. Quorum sensing in P. aeruginosa is a model to study cooperative behaviors in populations. Several studies of cooperation have been conducted using strain PAO1. Wild-type PAO1 harbors a mutation in mexS, which encodes a negative regulator of the transcription...

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Identifiers

PMID: 42017699
DOI: 10.1128/jb.00434-25
PMCID: PMC13182392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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