Article
PtxR modulates the expression of QS-controlled virulence factors in the Pseudomonas aeruginosa strain PAO1.
Molecular microbiology - 1 Aug 2006
Carty Nancy L, Layland Nancy, Colmer-Hamood Jane A, Calfee M Worth, Pesci Everett C, Hamood Abdul N
Abstract excerpt
The production of several virulence factors by Pseudomonas aeruginosa is regulated through the hierarchical cell-density dependent quorum sensing (QS) systems las and rhl. A third component of the QS hierarchy, the Pseudomonas quinolone signal PQS, also controls the expression of several genes. We previously described P. aeruginosa PtxR as a transcriptional activator of the exotoxin A gene toxA. Here, we provide...
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