Article
Cytokine polymorphisms in patients with autoimmune hemolytic anemia.
Frontiers in immunology - 1 Jan 2023
Zaninoni Anna, Fattizzo Bruno, Pettine Loredana, Vercellati Cristina, Marcello Anna P, Barcellini Wilma
Abstract excerpt
Autoimmune hemolytic anemia (AIHA) is due to autoantibodies with or without complement activation and involves cellular and cytokine dysregulation. Here, we investigated cytokine single-nucleotide polymorphisms (SNPs) of TNF-α, TGF-β1, IL-10, IL-6, and IFN-γ, along with their serum levels. The former were related to hematological parameters, therapy, and clinical outcome. The study included 123 consecutive...
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