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Article

Association of IL-10 and TGF-beta cytokine gene polymorphisms with autoimmune hepatitis.

Clinics and research in hepatology and gastroenterology - 1 Feb 2019

Yousefi Azizollah, Zare Bidoki Alireza, Shafioyoun Arezou, Sadr Maryam, Varzaneh Farnaz Najmi, Shabani Mahsima, Motamed Farzaneh, Farahmand Fatemeh, Khodadad Ahmad, Fallahi Gholamhossein, Najafi Mehri, Rezaei Nima

Abstract excerpt

BACKGROUND AND AIMS: Autoimmune hepatitis is a chronic immune-mediated liver injury caused by dysregulated immune response to liver antigens. Genetic susceptibility is affected by multiple single nucleotide polymorphisms in immune-related genes. There are few reports on the association of TGF-β and IL-10 genetic variants with autoimmune hepatitis. METHODS: Allele frequency and genotype status of IL-10 -1082,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30143451
DOI: 10.1016/j.clinre.2018.07.004

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