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Article

Impact of cytokine gene polymorphisms on risk and treatment outcomes of aplastic anemia.

Annals of hematology - 1 May 2011

Lee Yun-Gyoo, Kim Inho, Kim Jin Hee, Bae Ji-Yeon, Kwon Ji-Hyun, Shin Dong-Yeop, Lee Jong-Eun, Song Eun Young, Kim Hyun Kyoung, Yoon Sung-Soo, Park Sung Sup, Lee Dong Soon, Han Kyou-Sup, Park Myoung Hee, Hong Yun-Chul, Park Seonyang, Kim Byoung Kook

Abstract excerpt

Autoreactive cytotoxic T cells play a key role in the pathogenesis of aplastic anemia (AA) by myelosuppressive cytokines including interferon-gamma, tumor necrosis factor alpha, and transforming growth factor beta. The purpose of this study is to determine which single nucleotide polymorphisms (SNPs) in cytokine genes were relevant to AA risk and whether the relevant SNPs were associated with response to...

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Source

Identifiers

PMID: 20953611
DOI: 10.1007/s00277-010-1102-2

Genes

IFNG
TGFB1
FAS
TNF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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