Article
Cytokine polymorphisms in sickle cell disease and the relationship with cytokine expression.
Experimental hematology - 1 Jul 2016
Olenscki Gilli Simone Cristina, Pericole Fernando Vieira, Benites Bruno Deltreggia, Sippert Emilia Ângela, Castilho Lilian Maria, Addas-Carvalho Marcelo, Olalla Saad Sara Teresinha
Abstract excerpt
Sickle cell disease is a chronic inflammatory condition characterized by elevated levels of inflammatory cytokines, which may be regulated by genetic polymorphisms and could be associated with diverse disease presentations and alloimmunization. The aim of this study was to evaluate Treg and Th17 cell frequencies, cytokine gene polymorphisms, and their association with cytokine expression profile in patients with...
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