Inflammatory Cytokine Dysregulation and Interleukin Gene Polymorphisms in Iraqi Pediatric Sickle Cell Anemia: Implications for Genetic Risk Stratification and Targeted Therapy.

doi:10.1002/1545-5017.70425

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Inflammatory Cytokine Dysregulation and Interleukin Gene Polymorphisms in Iraqi Pediatric Sickle Cell Anemia: Implications for Genetic Risk Stratification and Targeted Therapy.

Pediatric blood & cancer - 1 Sept 2026

Hamzah Sundus K, Hoidy Wisam H

Abstract excerpt

BACKGROUND: Sickle cell anemia (SCA) involves inflammation that worsens disease symptoms and complications. The inflammatory profiles and genetic determinants among the pediatric Iraqi population are not well described. The current study aimed to analyze pediatric SCA in Iraq for cytokine dysregulation and interleukin gene polymorphism. PROCEDURE: A case-control study was performed involving 216 pediatric SCA...

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Anemia, Sickle Cell
Case-Control Studies
Child, Preschool
Cytokines
Inflammation
Interleukins
Iraq

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PMID: 42487332
DOI: 10.1002/1545-5017.70425

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