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Article

Polymorphisms in TNF and IFNG are associated with clinical characteristics of aplastic anemia in Argentinean population.

Leukemia & lymphoma - 1 Jun 2015

Bestach Yesica, Sieza Yamila, Attie Myriam, Riccheri Cecilia, Verri Verónica, Bolesina Moira, Bengió Raquel, Larripa Irene, Belli Carolina

Abstract excerpt

The impaired hematopoiesis in acquired aplastic anemia (AA) results from immune-mediated mechanisms. We characterized polymorphisms implicated in controlling type-1 cytokine production in 69 patients with AA. Our data suggest that the studied polymorphisms are not associated with susceptibility in the overall AA population. However, the presence of the higher expressing TNF - 308A allele was associated with...

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Source

Identifiers

PMID: 25248876
DOI: 10.3109/10428194.2014.966707

Genes

TNF
IFNG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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