Article
The association of cytokine genes polymorphisms and susceptibility to aplastic anemia in Egyptian patients.
Hematology (Amsterdam, Netherlands) - 1 Mar 2016
Zayed Rania A, Abdel-Hamid Samah M, El-Lithy Hend
Abstract excerpt
BACKGROUND AND OBJECTIVE: Aplastic anemia (AA) remains a rare disease, with very interesting pathophysiology that is being investigated for years now. The present study aimed to determine the association between cytokine gene polymorphisms (TGF-β1 -509 C/T, TNF-α -308 G/A, IFN-γ +874 A/T) and susceptibility to AA in Egyptian patients. METHODS: The study included 80 participants subjected to determination of gene...
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