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Article

Interleukin-10 promoter variability is associated with the susceptibility, severity, and clinical outcomes of aplasitc anemia in Han-Chinese population.

International journal of laboratory hematology - 1 Apr 2023

Wang Shichong, You Yahong, Ge Meili, Shao Yingqi, Huo Jiali, Ren Xiang, Li Xingxin, Huang Jinbo, Zhang Jing, Wang Min, Nie Neng, Jin Peng, Zheng Yizhou

Abstract excerpt

INTRODUCTION: Acquired aplastic anemia (AA), a heterogeneous bone marrow (BM) failure disease, is mainly mediated by the immune destruction of hematopoietic stem cells (HSCs). Given the predominant role of immunosuppressive therapy (IST) in AA, it is sensible to theorize that variants of cytokine genes might affect the outcome of IST. METHODS: In this study, we analyzed three single nucleotide polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36397188
DOI: 10.1111/ijlh.13993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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