Article
Interleukin 10 (IL10) promoter region polymorphism is associated with IL10 serum concentrations and processing speed in healthy community-dwelling older adults.
Behavioural brain research - 26 Feb 2024
Keegan Andrew P, Savage Karen, Bousman Chad A, Nolidin Karen, Cribb Lachlan, Pipingas Andrew, Stough Con
Abstract excerpt
Inflammation is repressed by interleukin 10 (IL10), a potent anti-inflammatory cytokine, and unchecked inflammation can have detrimental effects on cognition. In healthy older adults enrolled in the Australian Research Council Longevity Intervention (ARCLI) cohort we explored whether a known functional single nucleotide polymorphism (SNP) in the promoter region of IL10, -1082 G/A (rs1800896), was associated with...
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