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Article

Association of TLR4 with Alzheimer's disease risk and presymptomatic biomarkers of inflammation

4 Jun 2019

Abstract excerpt

INTRODUCTION: A coding variant in the TLR4 receptor (rs4986790), previously associated with longevity and Alzheimer's disease (AD) risk reduction, was examined in a population isolate (Québec Founder Population [QFP]) and in presymptomatic individuals with a parental history of AD (Pre-Symptomatic Evaluation of Novel or Experimental Treatment for Alzheimer's Disease [PREVENT-AD]). METHODS: Genotyping was...

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PMID: 31175027
DOI: 10.1016/j.jalz.2019.03.012

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