Article
Polymorphisms in cytokine genes influence cognitive and functional performance in a population aged 75 years and above.
International journal of geriatric psychiatry - 1 Dec 2017
Fraga Vanessa G, Guimarães Henrique C, Teixeira Antônio L, Barbosa Maira T, Carvalho Maria G, Caramelli Paulo, Gomes Karina B
Abstract excerpt
OBJECTIVE: To investigate the frequency of the cytokine single nucleotide polymorphisms (SNPs) tumor necrosis factor (TNF)-α -308G > A, tumor growth factor (TGF)-β1 codon +10C > T, TGF-β1 codon +25G > C, interleukin (IL)-10 -1082A > G, IL-10 -819C > T, IL-10 -592C > A, IL-6 -174G > C, and IFN-γ +874T > A in a sample of healthy and cognitively impaired elderlies and to verify the probable association between these...
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