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Article

Association between inflammation and cognition: Triangulation of evidence using a population-based cohort and Mendelian randomization analyses.

Brain, behavior, and immunity - 1 May 2023

Slaney Chloe, Sallis Hannah M, Jones Hannah J, Dardani Christina, Tilling Kate, Munafò Marcus R, Davey Smith George, Mahedy Liam, Khandaker Golam M

Abstract excerpt

BACKGROUND: Inflammation is associated with cognitive functioning and dementia in older adults, but whether inflammation is related to cognitive functioning in youth and whether these associations are causal remains unclear. METHODS: In a population-based cohort (Avon Longitudinal Study of Parents and Children; ALSPAC), we investigated cross-sectional associations of inflammatory markers (C-reactive protein...

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Identifiers

PMID: 36791891
DOI: 10.1016/j.bbi.2023.02.010
PMCID: PMC10728829

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