Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Associations between IL-1β, IL-6, and TNFα polymorphisms and longitudinal trajectories of cognitive function in non-demented older adults

29 Jun 2024

Abstract excerpt

Inflammation is implicated in Alzheimer's disease (AD), and specific single nucleotide polymorphisms (SNPs) in inflammatory cytokine genes are associated with increased AD risk. Whether the same polymorphisms also predict domain-specific cognitive change in cognitively healthy older adults is unclear. Specific SNPs in three cytokine genes, IL-1β (rs16944), IL-6 (rs1800795), and TNFα (rs1800629) were assessed for...

Read the complete abstract on PubMed

Topics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Dementia and Cognitive Impairment Research
Share to Neuroinflammation and Neurodegeneration Mechanisms

Source

Identifiers

PMID: 39055623
DOI: 10.1016/j.bbih.2024.100816

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations between IL-1β, IL-6, and TNFα polymorphisms and longitudinal trajectories of cognitive function in non-demented older adultsPMID 39055623Read ↗

A systematic review on the association between inflammatory genes and cognitive decline in non-demented elderly individuals.Semantic proximity Read ↗

Plasma IL-6 levels and their association with brain health and dementia risk: A population-based cohort study.Semantic proximity Read ↗

Associations between polymorphisms in five inflammation-related genes and cognitive ability in older persons.Semantic proximity Read ↗

Polymorphisms in cytokine genes influence cognitive and functional performance in a population aged 75 years and above.Semantic proximity Read ↗

Circulating interleukin-6 concentration and cognitive decline in old age: the PROSPER study.Semantic proximity Read ↗

CSF inflammatory cytokines as prognostic indicators for cognitive decline across Alzheimer’s disease spectrumSemantic proximity Read ↗

Commonly studied polymorphisms in inflammatory cytokine genes show only minor effects on mortality and related risk factors in nonagenarians.Semantic proximity Read ↗

CSF biomarkers of immune activation and Alzheimer’s disease for predicting cognitive impairment risk in the elderlySemantic proximity Read ↗

Interleukin-6 gene (-174 C/G ) and apolipoprotein E gene polymorphisms and the risk of Alzheimer disease in a Polish population.Semantic proximity Read ↗

Genetic priming of a proinflammatory profile predicts low IQ in octogenarians.Semantic proximity Read ↗

Association of IL-1β, IL-1α and IL-10 single nucleotide polymorphisms with Mini-Mental State Examination and event-related potentialsSemantic proximity Read ↗

Inflammatory Cytokines and Alzheimer's Disease: A Review from the Perspective of Genetic Polymorphisms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.