Article

Role of Inflammation in Depressive and Anxiety Disorders, Affect, and Cognition: Genetic and Non-Genetic Findings in the Lifelines Cohort Study

2024-04-19

Abstract excerpt

<h4>Background</h4> Low-grade systemic inflammation is implicated in the pathogenesis of various neuropsychiatric conditions affecting mood and cognition. While much of the evidence concerns depression, large-scale population studies of anxiety, affect, and cognitive function are scarce. Importantly, causality remains unclear. We used complementary non-genetic, genetic risk score (GRS), and Mendelian randomizatio...

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Literature Corpus work: 1b45c93c-641b-5a06-995d-650d87b72b12
DOI: 10.1101/2024.04.17.24305950

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