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Article

Circulating interleukin-6 concentration and cognitive decline in old age: the PROSPER study.

Journal of internal medicine - 1 Jul 2013

Mooijaart S P, Sattar N, Trompet S, Lucke J, Stott D J, Ford I, Jukema J W, Westendorp R G J, de Craen A J M

Abstract excerpt

BACKGROUND: Inflammation is involved in the pathogenesis of cardiovascular disease and cognitive decline. Interleukin-6 (IL-6) has a role in cardiovascular disease, but the association of IL-6 concentration and the functional IL-6 -174 polymorphism with cognitive decline has not been demonstrated unequivocally. The objective of this study was to investigate the associations between both high concentration of IL-6...

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PMID: 23414490
DOI: 10.1111/joim.12052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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