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Article

Identification of hepatoblastoma susceptibility loci in the TRMT6 gene from a seven-center case-control study.

Journal of cellular and molecular medicine - 1 Jan 2024

Ma Lin, Zhu Jinhong, Zhang Jiao, Zhang Wenli, Li Yong, Yang Zhonghua, Li Suhong, Cheng Jiwen, Li Li, He Jing, Liu Peng

Abstract excerpt

Hepatoblastoma, the most frequently diagnosed primary paediatric liver tumour, bears the lowest somatic mutation burden among paediatric neoplasms. Therefore, it is essential to identify pathogenic germline genetic variants, especially those in oncogenic genes, for this disease. The tRNA methyltransferase 6 noncatalytic subunit (TRMT6) forms a tRNA methyltransferase complex with TRMT61A to catalyse adenosine...

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Identifiers

PMID: 37850543
DOI: 10.1111/jcmm.18006
PMCID: PMC10805499

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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