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Article

m6A-SNPs identified by integrating genomic data are associated with the occurrence and prognosis of HCC.

Scientific reports - 27 Apr 2026

Yang Yi, Zhao Yue, Li Chenxi, You Chenghong, Zhang Xia, Zhou Henan, Zhao Wenhui, Liu Guoxiang, Fu Songbin, Wang Xi, Sun Wenjing, Zhang Xuelong

Abstract excerpt

N6-methyladenosine (m6A), a prevalent mRNA modification, plays a key role in cancer. m6A-associated single nucleotide polymorphisms (m6A-SNPs) have been implicated in various diseases, but their role in Hepatocellular Carcinoma (HCC) is unclear. This study aimed to identify HCC-related m6A-SNPs and validate their clinical relevance. We integrated HCC genome-wide association study (GWAS) data with the RMVar...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42045606
DOI: 10.1038/s41598-026-50598-9
PMCID: PMC13284384

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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