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Article

Association of RNA m7G Modification Gene Polymorphisms with Pediatric Glioma Risk.

BioMed research international - 1 Jan 2023

Zhu Jinhong, Liu Xiaoping, Chen Wei, Liao Yuxiang, Liu Jiabin, Yuan Li, Ruan Jichen, He Jing

Abstract excerpt

Glioma stemming from glial cells of the central nervous system (CNS) is one of the leading causes of cancer death in childhood. The genetic predisposition of glioma is not fully understood. METTL1-WDR4 methyltransferase complex is implicated in tumorigenesis by catalyzing N7-methylguanosine (m7G) modification of RNA. This study is aimed at determining the association of glioma risk with three polymorphisms...

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Case-Control Studies
Child
Genetic Predisposition to Disease
Glioma
GTP-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 36733406
DOI: 10.1155/2023/3678327
PMCID: PMC9889142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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