Article
METTL14 gene polymorphisms influence hepatoblastoma predisposition in Chinese children: Evidences from a seven-center case-control study.
Gene - 30 Jan 2022
Chen Huitong, Chen Zhen, Wang Mi, Zhang Jiao, Li Yong, Li Li, Li Suhong, Cheng Jiwen, Wang Xianqiang, Xia Huimin, Yang Zhonghua, He Jing
Abstract excerpt
Hepatoblastoma as the most prevalent hepatic malignancy in children, its etiology remains unclear. N6-Methyladenosine (m6A) modification which can modify various physiological processes, plays a critical role in tumorigenesis. Methyltransferase-like 14 (METTL14), an important component of the m6A methyltransferase complex, remains elusive during hepatoblastoma occurrence and development. We explored the...
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