Article
TRMT6 gene rs236110 C > A polymorphism increases the risk of Wilms tumor.
Gene - 5 Oct 2023
Chang Xiaofeng, Zhu Jinhong, Hua Rui-Xi, Deng Changmi, Zhang Jiao, Cheng Jiwen, Li Suhong, Zhou Haixia, He Jing, Wang Huanmin
Abstract excerpt
tRNA methyltransferase 6 (TRMT6)is an enzyme catalyzing N1-methyladenosine, a reversible modification in RNA, including tRNA, mRNA, rRNA, and lncRNA. Increasing evidence has shown the implications of this post-transcriptional modification and its regulators in carcinogenesis. However, its roles in Wilms tumor haven't been reported. In this study, four TRMT6 gene polymorphisms (rs236170 A > G, rs451571 T > C,...
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